Mixed connective tissue disease, as first described in 1972, is “classically” considered as an “overlap” of three diseases, systemic lupus erythematosus, scleroderma, and polymyositis. Patients with this pattern illness have features of each of these three diseases. They also typically have very high quantities of antinuclear antibodies (ANAs) and antibodies to ribonucleoprotein (anti-RNP) detectable in [...]
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Pain in the area of the coccyx (tailbone) is called coccydynia or coccygodynia (or sometimes a variety of other spellings). Coccydynia can be anything from discomfort to acute pain, varying between people and varying with time in any individual. The name describes a pattern of symptoms (pain brought on or aggravated by sitting), so it [...] For patients with systemic lupus erythematosus, depression further increases their already elevated risk for cardiovascular disease, researchers said here. In these patients, depression was associated with a nearly four-fold greater risk of subclinical atherosclerosis (OR 3.85, 95% CI 1.37 to 10.87), Carol Greco, PhD, of the University of Pittsburgh, reported at the meeting of the [...] |
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